Scientific Program

Programação Final: Neuro-ImunoMetabolismo em Obesidade e Doenças Metabólicas

26 October 2018 (Friday)

8:30 – 9:15 h Registration, Opening Session. Joana Gaspar

9:15 – 10:00 h Opening Seminar: Functional development of neuronal mechanisms in the control of metabolism. Marcelo Dietrich

10:00 – 10:30h Coffee Break

10:30 – 11:30 h: Oral Presentations (10 min)

– Leptin modulates body composition and hypothalamic gene expression in mice from the second week of life. Pryscila Teixeira

– Metabolic and glycemic effects of growth hormone receptor deletion in POMC neurons. Paula Quaresma

– Evaluation of the ability of IL-6 to induce neuronal differentiation in cells from hypothalamic neurogenic niche. Vanessa Bóbbo

– GPR40 receptor activation promotes cell proliferation in the hypothalamus of adult mice. Daiane Engel

– Knockdown of Nhlh2 in arcuate nucleus promotes body weight gain in mice. Rodrigo Scarpari Carraro

– Hypothalamic gene profile related to reproduction and metabolism during development. Tabata M. Bohlen

11:30 – 12:15h: Molecular targets of methylglyoxal and its effect on mood and cognition. Alcir Dafre

12:15 – 14:00 Lunch

14:00 – 14:45: 6-OHDA treatment does not affect the glucose and lipid homeostasis in male rats Alex Rafacho

14:45 – 15:30: Molecular links between diabetes and Alzheimer’s disease. Fernanda De Felice

15:30 – 16:00: Coffee Break

16:00 – 17:30: Oral Presentations (10 min)

– Palmitate effects on the pathogenesis of sporadic Alzheimer’s disease. Helen Melo

– Short-term high-fat diet consumption increases the Alzheimer’s disease pathogenic proteins in the hippocampus. Vitor Rosetto Muñoz

– Study of the acute effect of chalcones on glycemic, lipid and insulinemic response. Paola Miranda Sulis

– Alterations in CD300f immunoreceptor are associated to Major Depressive Disorder in mice and humans. Fernanda Neutzling Kaufmann

– The role of 1,25(OH)2 vitamin D3 on glucose homeostasis on target tissues of insulin. Ana Karla Mendes

– Effects of the use of antibiotic prophylaxis in childhood undernutrition over gut microbiota and the immune system. Gabriela Farias Gubert

– Social recognition memory impairment and depressive-like behavior in middle-aged hypercholesterolemic mice and intervention with caffeine. Jozimar Carlos Szczepanik

17:30 -18:15h: Impact of insulin-resistant diabetes on the energy metabolism of neurons and astrocytes. João Duarte

27 October 2018 (Saturday)


9:30 – 10:15 h Hypothalamic inflammation in obesity. Lício A. Velloso

10:15 – 11:00 h Finding new players in the hypothalamus to fight obesity. Cláudia Cavadas

11:00 – 11:30 h Coffee Break

11:30 – 12:45 h: Oral Presentations (10 min)

– Long-term exposure to high glucose concentrations and its derivatives promotes mitochondrial dysfunction in astroglial cells. Naiara Lucredi

– Effects of Peptide 19 (Pep19) on high-fat diet-induced obesity in mice. Renata Silvério

– Autophagy is induced after palmitate treatment in mHypoE-46 and mHypoA 2-29 hypothalamic cell lines. Andressa Reginato

– Gender related differences of hypercholesterolemia-induced memory deficits in a genetic model of familial hypercholesterolemia. Gislaine Olescowicz

–  Influence of Interleukin-17 in hypothalamic POMC expression and feeding behavior in mice. Guilherme Nogueira

– Evaluation of the antidepressant effect of the hydroalcoholic extract of rapanea ferrugnea barks and isolated compounds in hyperglycemic animals. Priscila Laiz Zimath

-Transcranial Direct-Current Stimulation modulates neuroinflammatory, behavioral and biometric parameters in Wistar rats submitted to diet-induced obesity. Josimar Macedo de Castro

12:45 – 14:30 Almoço

14:30 – 15:15 h Deep Brain Stimulation (DBS) in obesity: opportunities and challenges. Roger Walz

15:15 – 16:00: Metabolic derangements predisposing to neurodegenerative disease: Selenium compounds as a promising therapy. Andreza Fabro de Bem

15:30 – 16:00 Coffee Break

16:00 – 16:45 Chronic Metabolic Derangement-Induced Cognitive Deficits and Neurotoxicity Are Associated with REST Inactivation. Alexandra Latini

16:45 – 17:30h Mitochondrial dynamics in POMC neurons: a key nexus for metabolic health.  Marc Claret

17:30h – Encerramento. Entrega de prêmios. Joana M.Gaspar